INTERNAL ASSESSMENT

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Clinical Complexity in Neurodegenerative Diseases - Case Series

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INTRODUCTION The term neuro - referring the cells of brain /neurons, Degeneration- deterioration and loss of function in the cells of a tissue or organ. These disorders are an umbrella term for a spectrum of diseases that can cause symptoms ranging from mood disturbances to dementia, involuntary movements, and cognitive decline that affect daily life. The lack of clear criteria for defining neurodegenerative disorders means that there is a wide variety of etiologies and pathophysiology to understand the clinical, pathological, molecular pathways, and therapeutic targets in management. This creates a broad scope for future research and treatment advancements. This can make it challenging to diagnose and treat these diseases effectively. However, researchers are working to better understand the underlying mechanisms of neurodegenerative disorders, which could lead to more effective treatments in the future. Neurodegenerative disorders can impact many different facets of functioning, ...
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A 70 yo Female with Neck Muscle Stiffness and Loss of Speech

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A 70 year old female came with complaints of neck muscle stiffness and unable to speak. HISTORY OF PRESENT ILLNESS: Patient was apparently asymptomatic 7 yrs back. Then she developed pain in right shoulder for which she was managed conservatively. 5 yrs ago, she developed weakness and giddiness and was diagnosed with HTN. Since 5 yrs, she developed pain in both lower limbs. PAST HISTORY: k/c/o HTN No history of DM. No history of TB. No history of Bronchial asthma. PERSONAL HISTORY: Diet: Mixed Appetite: Decreased Adequate sleep Bowel & bladder movements: Normal and Regular TREATMENT HISTORY: 1. TAB. ATENOLOL 25mg  2. TELMA-40  3. TAB. ACECLOPHENAC 4. TAB. PREDNISOLONE 5mg GENERAL EXAMINATION: Pt. is conscious Pallor is seen No icterus No cyanosis No clubbing No lymphadenopathy No pedal edema                                                   ...
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53F With Uncontrolled Hand Movements

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NOTE: THIS IS AN ONLINE E LOGBOOK TO DISCUSS OUR PATIENT'S DE-IDENTIFIED HEALTH DATA SHARED AFTER TAKING HIS/HER GUARDIAN'S SIGNED INFORMED CONSENT. HERE WE DISCUSS OUR INDIVIDUAL PATIENT'S PROBLEMS THROUGH A SERIES OF INPUTS FROM THE AVAILABLE GLOBAL ONLINE COMMUNITY OF EXPERTS INTENDING TO SOLVE THOSE CLINICAL PROBLEMS WITH COLLECTIVE CURRENT BEST EVIDENCE-BASED INPUT. A 53F woman, who works as a teacher complains of uncontrolled movements in fingers and toes since 7 years.  HISTORY OF PRESENT ILLNESS: Patient was apparently asymptomatic 7 years back. She then developed slight movements in her fingers and toes that were not under her control. These movements lasted for 10-15 minutes and occurred 2-3 times in an hour. The frequency has now increased. There is no associated weakness. These tremors are of low amplitude and high frequency. They are also present during sleep. Episodic in nature. Occur and resolve spontaneously. No triggers. Aggravated on stretching arms. No re...
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