INTERNAL ASSESSMENT

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Clinical Complexity in Neurodegenerative Diseases - Case Series

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INTRODUCTION The term neuro - referring the cells of brain /neurons, Degeneration- deterioration and loss of function in the cells of a tissue or organ. These disorders are an umbrella term for a spectrum of diseases that can cause symptoms ranging from mood disturbances to dementia, involuntary movements, and cognitive decline that affect daily life. The lack of clear criteria for defining neurodegenerative disorders means that there is a wide variety of etiologies and pathophysiology to understand the clinical, pathological, molecular pathways, and therapeutic targets in management. This creates a broad scope for future research and treatment advancements. This can make it challenging to diagnose and treat these diseases effectively. However, researchers are working to better understand the underlying mechanisms of neurodegenerative disorders, which could lead to more effective treatments in the future. Neurodegenerative disorders can impact many different facets of functioning, ...
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CKD secondary to NSAID abuse

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   THIS IS AN ONLINE E LOG BOOK TO DISCUSS OUR PATIENT'S DE - IDENTIFIED HEALTH DATA SHARED AFTER TAKING HIS / HER /GUARDIAN'S SIGNED INFORMED CONSENT .HERE WE DISCUSS OUR INDIVIDUAL PATIENT'S PROBLEMS THROUGH SERIES OF INPUTS FROM AVAILABLE GLOBAL ONLINE COMMUNITY OF EXPERTS WITH AN AIM TO SOLVE THOSE CLINICAL PROBLEMS WITH COLLECTIVE CURRENT BEST EVIDENCE BASED INPUT.    This E blog also reflects my patient centered online learning portfolio and your valuable inputs on the comment box is welcome I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan. A 29 year male came to opd with chief complaints of  Bilateral pain in lower limbs upto knee since 20 days HOPI Patient was apparently asymptomatic 3 years ago then developed severe sudden pain...
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28M painful polyneuropathy, skin lesions and recurrent quadriparesis, alcoholism

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A 28 yr old male came with chief complaints of: - Weakness of both lower limbs since 15 days - multiple ulcers all over the body since 5 days HOPI: Pt. was apparently asymptomatic 15 days back, then he noticed weakness in both lower limbs when he was trying to wake up in the morning, which was sudden in onset, gradually progressive, associated with b/l limb pains.  H/o difficulty in climbing stairs, standing from sitting position. No h/o difficulty in combing, wearing T shirt, buttoning/unbuttoning. H/o high grade, intermittent fever since 5 days. Associated with chills, generalized weakness. H/o ulcers all over the body since 5 days, initially blisters, later ruptured. No h/o difficulty in coitus Patient then went to local RMP, where he was given Diclofenac and Monocef injections for 3 days.   PAST HISTORY: H/o similar complaints of weakness of both lower limbs 4 times in the past - diagnosed as ?hypokalemic periodic paralysis N/k/c/o DM, HTN, CAD, CVD, epilepsy, thyroid...
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